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A study examining the relationship between PFKB3 and sorafenib resistance in HCC cells and a subcutaneous xenograft model in nude mice revealed that high PFKB3 expression and glycolysis contribute to sorafenib resistance
Ethics statement The studies involving humans were approved by the Institutional Review Board of BRANY IRB-Manager, New York, United States
Some users have also reported experiencing increased anxiety or restlessness, particularly when taking higher doses
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These effects are often related to the stress that extended fasting places on the hypothalamic-pituitary-gonadal (HPG) axis, the hormonal system that regulates reproductive function
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